从临床需求出发，寻找研究问题，以工程的原理、方法和技术解决未满足的临床需求。

研究方向：

• 基础研究：生物医学工程领域中的建模仿真+动物实验，分析物理效应对治疗效果的影响，如电场和热场

• 工程实现：有源医疗设备研制，如多源心脏射频消融仪、心脏微秒脉冲电场消融仪

• 算法方面：心腔内电位特征判别心律失常疾病(与企业合作)

近年主持/参与研究项目

国家重点研发项目，子课题

国家自然科学基金青年基金，负责人

上海市药品和医疗器械不良反应监测中心（横向课题），负责人

复旦大学人才引进项目

中国博士后面上项目，负责人

上海市经信委项目1项（项目高级研究人员），参与

上海市科委项目2项（项目高级研究人员），参与

论文

[1] Yan Shengjie, Gu Kaihao, Wu Xiaomei^*, Wang Weiqi. Computer simulation study on the effect of electrode–tissue contact force on thermal lesion size in cardiac radiofrequency ablation. International journal of Hyperthermia.2020, 37(1):37-48

[2] Yan Shengjie, Wu Xiaomei, Wang Weiqi. Theoretical and experimental analysis of amplitude control ablation and bipolar ablation in creating linear lesion and discrete lesions for treating atrial fibrillation. International Journal of Hyperthermia, 2017,33(6):608-616.

[3] Yan Shengjie, Wu Xiaomei, Wang Weiqi. A simulation study to compare the phase-shift angle radiofrequency ablation mode with bipolar and unipolar modes in creating linear lesions for atrial fibrillation ablation. International Journal of Hyperthermia, 2016, 32(3):231-238. 

[4] Yan Shengjie, Gu Kaihao, Wang Weiqi, Wu Xiaomei^*. Computational Modeling of Myocardial Thermal lesion Induced by Multi-source Frequency Control RF ablation Method. 2020 10th International Conference on Bioscience, Biochemistry and Bioinformatics. 2020,90-95

[5] Yan Shengjie, Wu Xiaomei, Wang Weiqi. Computer simulation study on comparing lesion effects of radio frequency ablation for treating atrial fibrillation by multichannel bipolar or unipolar. The 9th International Conference on Future Computer and Communication, 2017,1379-1386

[6]Gu Kaihao, Wang Yiheng, Yan Shengjie*, Wu Xiaomei*. Effect of anisotropy in myocardial electrical conductivity on lesion characteristics during radiofrequency cardiac ablation: a numerical study. International Journal of Hyperthermia.2022,39(1):120-133

[7] Gu Kaihao, Wang Yiheng, Yan Shengjie^*, Wu Xiaomei^*. Modeling Analysis of Thermal Lesion Characteristics of Unipolar Bipolar Ablation Using Circumferential Multipolar Catheter. Applied sciences. 2020,10,9081

[8] 赵燕，鄢盛杰，邬小玫，用于房颤治疗的射频消融技术进展. 中国医疗器械杂志.2018, 42(5):350-353.

专利

鄢盛杰，邬小玫，实现线性消融的可调射频相位差功率放大电路，发明型(已授权)

鄢盛杰，邬小玫，顾恺灏，基于幅值可控的多路射频消融系统，发明型(已授权)

鄢盛杰，邬小玫，顾恺灏，基于频率可控的多源射频消融系统，发明型(已受理)